Studies with polyfunctionality substituted heterocycles: Novel syntheses of thienopyrimido-1, 2, 4-triazoles

ABA El-Gazzar, MI Hegab, SA Swelam…

文献索引：El-Gazzar; Hegab; Swelam; Aly Phosphorus, Sulfur and Silicon and Related Elements, 2002 , vol. 177, # 1 p. 123 - 136

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被引用次数: 14

摘要

Several 3-substituted-(un)-cyclohepta (b) thieno [2, 3-d] pyrimido [3, 4-a]-1, 2, 4-triazoles 10, 11, 12, 13, and 14 were prepared by reaction of an appropriate substituted 2-amino-3- cyanothiophene 1 with aliphatic acids or benzoyl chloride. Also the fusion of 1 with urea, thiourea to give the corresponding 2-oxo or thioxo-4-aminopyrimidine derivatives 6a, b and other reactions of compound 1 are reported.