Tetrahedron Letters

Formation of bi-aryls via a domino palladium catalysis

J Krishna, AGK Reddy, G Satyanarayana

文献索引：Krishna; Reddy, A. Gopi Krishna; Satyanarayana Tetrahedron Letters, 2014 , vol. 55, # 4 p. 861 - 864

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被引用次数: 11

摘要

Abstract Synthesis of bi-aryls via a domino Pd-catalyzed reaction of 1-(2-bromophenyl)-2- methylpropan-1-ones/(2-bromophenyl)(cyclohexyl) methanones is presented. The mechanism of the reaction is believed to proceed through a five membered palladacycle that combines with a second molecule of halo-arene to yield the bi-aryls. This method is quite successful to deliver highly sterically crowded bi-aryls with dense functionalities on the ...