Synthesis of 8, 9-(1, 3-benzodioxolo-5, 6)-5-azatricyclo [8.2. 1.01, 5] tridec-11-en-6-one. A convenient route to structural analogs of the alkaloid cephalotaxine
NY Kuznetsov, VN Khrustalev, YN Bubnov
文献索引:Kuznetsov; Zhun; Khrustalev; Bubnov Russian Chemical Bulletin, 2005 , vol. 54, # 9 p. 2229 - 2232
Abstract A synthetic route to 8, 9-(1, 3-benzodioxolo-5, 6)-5-azatricyclo [8.2. 1.0 1, 5] tridec- 11-en-6-one structurally isomeric to the pentacyclic cephalotaxine nucleus is suggested. The route is based on the sequence including diallylboration of 2-pyrrolidinone and