Synthesis

A facile approach to the synthesis of allylic spiro ethers and lactones

MCP Yeh, YC Lee, TC Young

文献索引：Yeh, Ming-Chang P.; Lee, Yi-Chin; Young, Tsao-Ching Synthesis, 2006 , # 21 p. 3621 - 3624

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被引用次数: 6

摘要

Abstract Treatment of 3-[(alkoxycarbonyl) alkyl]-substituted conjugated cycloalkenones with diisobutylaluminum hydride at-78 C followed by acid quenching furnishes spiro ethers, whereas the corresponding 3-(carboxyalkyl)-substituted cycloalkenones generate spiro lactones upon reaction with sodium borohydride at 30 C followed by acid quenching.