The synthesis and determination of acidic ionization constants of certain 5??substituted 2??aminopyrrolo [2, 3??d] pyrimidin??4??ones and methylated analogs

…, J Park, GA Garcia, LB Townsend

文献索引：Hoops, Geoffrey C.; Park, Julie; Garcia, George A.; Townsend, Leroy B. Journal of Heterocyclic Chemistry, 1996 , vol. 33, # 3 p. 767 - 781

全文：HTML全文

被引用次数: 16

摘要

770 G. С. Hoops, J. Park, GA Garcia, and LB Townsend Vol. 33 doublet for H-6 might be expected if N-7 was protonated. However, the signal for H-6 does not consistently appear as a doublet in the unmethylated or N-3-methylated analogs. The uv spectra (see Table 1) of these compounds are nearly identical to their corresponding unmethylated analogs. Methylation at Nl or O-alkylation to give the corresponding 4-methoxy analogs would be expected [12] to produce a ...