9-Amino derivatives of 4-azafluorene

NS Prostakov, VP Shalimov, HM Cordova…

文献索引：Prostakov, N. S.; Shalimov, V. P.; Cordova, Halo Montenegro; Leonova, N. I. Pharmaceutical Chemistry Journal, 1984 , vol. 18, # 11 p. 773 - 775 Khimiko-Farmatsevticheskii Zhurnal, 1984 , vol. 18, # 11 p. 1333 - 1335

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摘要

The development of a method for the Preparation of 4-azafluorene (I) by catalytic dehydro cyclization of 3-methyl-2-phenylpyridine [i] broadened the scope of investigations on the synthesis of derivatives of this heterocyclic system. We took into consideration the fairly large amount of information on the broad spectrum of physiological activity of different fluorene derivatives, in particular, 9-[(methyl-~-chloroethyl) amino] fluorene [4], and turned our ...