Tetrahedron Letters

γ-Methyl-substituted-γ-butyrolactones: solid-phase synthesis employing a cyclisation–cleavage strategy

N Gouault, JF Cupif, A Sauleau, M David

文献索引：Gouault; Cupif; Sauleau; David Tetrahedron Letters, 2000 , vol. 41, # 38 p. 7293 - 7297

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被引用次数: 45

摘要

The solid-phase synthesis of several γ-methyl-substituted-γ-butyrolactones using a cyclisation–cleavage reaction is reported. Chemical modifications of polymer-bound azido (2a) and iodo alcohols (2b) were realised in order to introduce additional diversity onto the lactone structure.