Synthesis, characterization and antimicrobial activity of bifunctional sulfonamide-amide derivatives

BRA Abbavaram, HRV Reddyvari

文献索引：Abbavaram, Babul Reddy A.; Reddyvari, Hymavathi R.V. Journal of the Korean Chemical Society, 2013 , vol. 57, # 6 p. 731 - 737

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被引用次数: 1

摘要

Abstract A convenient synthesis of bifunctional sulfonamide-amide derivatives was reported. Amide coupling of 4-methyl benzoic acid 1 followed by reaction with chlorosulfonic acid produce ethyl-4-(3-(chlorosulfonyl)-4-methylbenzoyl) piperazine-1-carboxylate 4. The resulted compound on further treatment with various anilines produces the title sulfonamide- amide derivatives 5a-n. The configurations of these compounds were established by ...