Tetrahedron letters

Coupling of β-acetamido radicals with α-chloro-acrylonitrile—a new access to disubstituted proline derivatives

R Henning, H Urbach

文献索引：Henning, R.; Urbach, H. Tetrahedron Letters, 1983 , vol. 24, # 48 p. 5343 - 5346

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被引用次数: 26

摘要

The configuration at C-2 of , and , could not be assigned unequivocally. However, strong evidence comes from the 1 H NMR spectra (60MHz, D 2 O) of amino acids and : The proton at C-5 shows up as a doublet of triplets (J 1 = 8Hz, J 2 = 6Hz) at 3.2 ppm for and a quartet (J = 6Hz) at 3.6 ppm for .This deshielding of the C-5 proton in is probably due to the carboxyl group's standing on the same side of the pyrrolidine ring, as indicated. ... Cookies are used by this site. To ...