Tetrahedron Letters 2018-04-07

Synthesis of benzyl halide derivatives of spirohydantoins via [2+2+2] cyclotrimerization reaction

Sanbasivarao Kotha, Gaddamedi Sreevani

文献索引：10.1016/j.tetlet.2018.04.012

摘要

Generally, synthesis of hydantoin derivatives involve use of carbonyl compounds which in turn require multistep synthesis. Here, we report a new approach to assemble spirohydantoins via [2+2+2] cyclotrimerization reaction using commercially available, inexpensive hydantoin as a starting material.