A new, simple synthesis of N-tosyl pyrrolidines and piperidines

…, V Campagna, S Sternativo, F Costantino, M Curini

文献索引：Marcotullio, Maria Carla; Campagna, Valerio; Sternativo, Silvia; Costantino, Ferdinande; Curini, Massimo Synthesis, 2006 , # 16 p. 2760 - 2766

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被引用次数: 21

摘要

Pyrrolidines and piperidines are important heterocyclic cores of several natural products [1] and, as such, have always attracted the attention of chemists. As a result of this interest, several synthetic methodologies have been developed, [2] with one of the most common being the cyclization of alkenes bearing an internal nucleophile, using electrophiles such as H + , Pd 2+ , PhS + or PhSe + . Iodocyclization of homoallylic tosylamides has been shown to be a smooth ...