An Inexpensive and Efficient Copper Catalyst for N??Arylation of Amines, Amides and Nitrogen??Containing Heterocycles

…, H Rao, H Fu, Y Jiang, Y Zhao

文献索引：Guo, Xun; Rao, Honghua; Fu, Hua; Jiang, Yuyang; Zhao, Yufen Advanced Synthesis and Catalysis, 2006 , vol. 348, # 15 p. 2197 - 2202

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被引用次数: 128

摘要

Abstract An inexpensive and efficient catalyst system has been developed for the N-arylation of nitrogen-containing compounds including a variety of amines, amides, indole and imidazole. This simple protocol uses CuI as the catalyst, commercial available pipecolinic acid as the new ligand, K 2 CO 3 as the base and DMF as the solvent.