Copper-catalyzed enantioselective carbenoid insertion into S–H bonds

YZ Zhang, SF Zhu, Y Cai, HX Mao…

文献索引：Zhang, Yong-Zhen; Zhu, Shou-Fei; Cai, Yan; Mao, Hong-Xiang; Zhou, Qi-Lin Chemical Communications, 2009 , # 36 p. 5362 - 5364

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被引用次数: 19

摘要

An asymmetriccarbenoidinsertion into S–H bonds catalyzed by copper–chiral spiro bisoxazoline complexes has been developed, in which a series of α-mercaptoesters were produced in high yields with moderate to good enantioselectivities (up to 85% ee); this result represents the best enantioselectivity in the catalytic asymmetriccarbenoid S–H bond insertion reaction.