Synthesis and evaluation of fluorinated analogues of monoamine reuptake inhibitors

…, J Kaffy, T Milcent, D Bonnet-Delpon

文献索引：Philippe, Christine; Kaffy, Julia; Milcent, Thierry; Bonnet-Delpon, Danile Journal of Fluorine Chemistry, 2012 , vol. 134, p. 136 - 145

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被引用次数: 2

摘要

The synthesis of two series of fluorinated analogues of monoamines reuptake inhibitors based on tertiary alcohols 2-substituted morpholines scaffold has been achieved through the incorporation of fluorinated substituent into 2-substituted morpholino ketones. Their binding affinities have been measured on different monoamine transporters.