The Journal of Organic Chemistry

Synthetic approach to versatile chiral molecules containing a fluorine atom

T Kitazume, Y Nakayama

文献索引：Kitazume, Tomoya; Nakayama, Yoshimichi Journal of Organic Chemistry, 1986 , vol. 51, # 14 p. 2795 - 2799

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被引用次数: 35

摘要

Our studies of the synthetic utility of fluor0 olefins have focused on the use of an extremely versatile building block in the preparations of a-fluorinated ketones, a group of compounds which reflect increasing interest in the molecular design concerning the biological activitie~.'- ~ However, no general stereocontrolled synthetic approach to chiral monofluorinated synthons, for a key process to achieve the above purpose, has been reported except a few ...