Hydrolytic Deallylation of N??Allyl Amides Catalyzed by PdII Complexes

N Ohmura, A Nakamura, A Hamasaki…

文献索引：Ohmura, Naoya; Nakamura, Asami; Hamasaki, Akiyuki; Tokunaga, Makoto European Journal of Organic Chemistry, 2008 , # 30 p. 5042 - 5045

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被引用次数: 13

摘要

Abstract Hydrolytic deallylation of N-allyl amides to give amides and propanal can be achieved with Pd II catalysts. The optimized catalyst consists of Pd (OCOCF 3) 2 and 1, 3-bis (diphenylphosphanyl) propane (DPPP). Several kinds of open-chain N-allyl amides and N- allyl lactams undergo hydrolytic deallylation to give the corresponding amides and lactams in good to high yield. A mechanism which includes isomerization to enamides and ...