Catalyst??Controlled Wacker??Type Oxidation of Protected Allylic Amines

…, JR McCombs, A Winkler, MS Sigman

文献索引：Michel, Brian W.; McCombs, Jessica R.; Winkler, Andrea; Sigman, Matthew S. Angewandte Chemie - International Edition, 2010 , vol. 49, # 40 p. 7312 - 7315

全文：HTML全文

被引用次数: 42

摘要

The Tsuji–Wacker oxidation provides access to methyl ketones from terminal olefins and is commonly utilized in complex molecule synthesis.[1] However, this reaction is under substrate control, which can lead to a mixture of aldehyde and ketone products, especially when the alkene bears a proximal heteroatom.[2, 3] An excellent example of exploiting this was recently reported by Feringa and co-workers wherein allylic phthalimides provided ...