Macroporous hydrogels upregulate osteogenic signal expression and promote bone regeneration

…, AB Yeatts, WJ Richbourg, JF Caccamese…

文献索引：Betz, Martha W.; Yeatts, Andrew B.; Richbourg, William J.; Caccamese, John F.; Coletti, Domenick P.; Falco, Erin E.; Fisher, John P. Biomacromolecules, 2010 , vol. 11, # 5 p. 1160 - 1168

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被引用次数: 62

摘要

The objective of this work was to investigate the effects of macroporous hydrogel architecture on the osteogenic signal expression and differentiation of human mesenchymal stem cells (hMSCs). In particular, we have proposed a tissue engineering approach for orbital bone repair based on a cyclic acetal biomaterial formed from 5-ethyl-5- (hydroxymethyl)-β, β-dimethyl-1, 3-dioxane-2-ethanol diacrylate (EHD) and poly (ethylene ...