Synthesis of Optically Active Heterocyclic Compounds by Preparation of 1, 3??Dinitro Derivatives and Enzymatic Enantioselective Desymmetrization of Prochiral …
…, E Busto, V Gotor??Fernández, V Gotor
文献索引：Rios-Lombardia, Nicolas; Busto, Eduardo; Gotor-Fernandez, Vicente; Gotor, Vicente European Journal of Organic Chemistry, 2010 , # 3 p. 484 - 493
Abstract A general approach for the highly efficient chemical preparation of novel optically active 2-substituted propane-1, 3-diamines is described. Diamines have been obtained from the corresponding commercially available aldehydes in a straightforward two-step synthesis via the corresponding 1, 3-dinitro compounds, which were hydrogenated under mild reaction conditions by using platinum dioxide as the catalyst. Subsequent enzymatic ...
