Catalysis letters

Synthesis of δ-and ε-Cyanoesters by Zinc-Catalyzed Ring-Opening of Cyclic Ethers with Acid Chlorides and Subsequent Cyanation

S Enthaler, M Weidauer

文献索引：Enthaler, Stephan; Weidauer, Maik Catalysis Letters, 2012 , vol. 142, # 2 p. 168 - 175

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被引用次数: 12

摘要

Abstract In the present study, the zinc-catalyzed cleavage of cyclic ethers with acid halides as nucleophiles to yield chloroesters with different chain length has been investigated in detail. In the presence of straightforward and commercially available zinc salts as pre- catalysts excellent yields and selectivities were feasible. After studying the reaction conditions and the scope of the method, several efforts were carried out to understand the ...