Photocyclisations de cétoacétals aromatiques en vue d'une approche synthétique de la crombénine

F Cottet, L Cottier, G Descotes

文献索引：Cottet, Francoise; Cottier, Louis; Descotes, Gerard Canadian Journal of Chemistry, 1990 , vol. 68, # 7 p. 1251 - 1257

全文：HTML全文

被引用次数: 0

摘要

Crombenin 1 is a spiropeltogynoid compound with a spiroacetal moiety. A similar structure was synthesized starting from an orthocarbonylphenoxyisochroman by a Norrish type II photocyclisation. With an isochroman compound, the aromatic ring induces benzyl radical formation to give chiefly a bicyclic [4.3. 1] derivative. However, with the introduction of electron-withdrawing or bulky substituents at C-4', this side reaction is limited and the ...