Synthesis and PKCθ inhibitory activity of a series of 5-vinyl phenyl sulfonamide-3-pyridinecarbonitriles

J Shim, C Eid, J Lee, E Liu, D Chaudhary…

文献索引：Bioorganic and Medicinal Chemistry Letters, , vol. 19, # 23 p. 6575 - 6577

全文：HTML全文

被引用次数: 12

摘要

... Bioorganic & Medicinal Chemistry Letters. ... Several chemical series have been shown to be ATP-competitive inhibitors of PKCθ including 2,4-diamino pyrimidines, 6 thieno[2,3-b]pyridinecarbonitriles 7, 8 and 9 and 3-pyridinecarbonitriles. ...