Organic letters

Site-Selective Pd-Catalyzed Coupling of 1, 4-Diiodo-1, 3-alkadienes with Grignard Reagents and Its Application to the Synthesis of Fulvenes

M Uemura, Y Takayama, F Sato

文献索引：Uemura, Minoru; Takayama, Yuuki; Sato, Fumie Organic Letters, 2004 , vol. 6, # 26 p. 5001 - 5004

全文：HTML全文

被引用次数: 17

摘要

The coupling reaction of 1, 4-diiodo-1, 3-alkadienes with a Grignard reagent in the presence of a catalytic amount of Pd (PPh3) 4 proceeded with excellent site-selectivity. Synthetic application of the reaction was demonstrated by a regio-and stereoselective synthesis of 1, 3, 6-trisubstituted fulvenes.