Synthesis and enzyme inhibitory activities of some new pyrazole-based heterocyclic compounds

T Harit, F Malek, B El Bali, A Khan, K Dalvandi…

文献索引：Harit, Tariq; Malek, Fouad; Bali, Brahim El; Khan, Ajmal; Dalvandi, Kourosh; Marasini, Bishnu P.; Noreen, Shagufta; Malik, Rizwana; Choudhary, M. Iqbal; Khan, Sadia Medicinal Chemistry Research, 2012 , vol. 21, # 10 p. 2772 - 2778,7

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被引用次数: 8

摘要

Abstract Three tridentate N, N-bis (3, 5-dimethylpyrazol-1-ylmethyl)-1-hydroxy-2- aminoethane (2), N, N-bis (3, 5-dimethylpyrazol-1-ylmethyl)-cyclohexylamine (3) and 2-[bis (1, 5-dimethyl-1 H-pyrazol-3-ylmethyl) amino] ethan-1-ol (4) are synthesized and spectroscopically characterized together with 1-hydroxymethyl-3, 5-dimethylpyrazole (1). These have been tested in inhibitory activities against various hyperactive enzymes like ...