Tetrahedron Letters

Lactone synthesis via the intramolecular alkylation of β-keto ester dianions

RJ Sims, SA Tischler, L Weiler

文献索引：Sims, Russell J.; Tischler, Samuel A.; Weiler, Larry Tetrahedron Letters, 1983 , vol. 24, # 3 p. 253 - 256

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被引用次数: 14

摘要

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Long chain ω-halo β-keto esters undergo intramolecular alkylation via the dianions to yield macrocylic β-keto lactones. ... Efforts to detect and isolate other products in this reaction have been unsuccessful as yet and the material balance is poor. However, these yields are comparable to those ...