New class of antitubercular compounds: synthesis and anti-tubercular activity of 4-substituted pyrrolo [2, 3-c] quinolines

M Akula, JP Sridevi, P Yogeeswari, D Sriram…

文献索引：Akula, Mahesh; Sridevi, Jonnalagadda Padma; Yogeeswari; Sriram; Bhattacharya, Anupam Monatshefte fur Chemie, 2014 , vol. 145, # 5 p. 811 - 819

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被引用次数: 6

摘要

Abstract Modified synthesis and antitubercular activity of 4-substituted pyrrolo [2, 3-c] quinolines are reported. Some of the compounds showed significant antitubercular activity, when compared to some of the existing antitubercular drugs. A compound with an imidazole moiety at position 4 shows the highest activity and least toxicity. Graphical abstract