Analgesic, anticonvulsant and anti-inflammatory activities of some synthesized benzodiazipine, triazolopyrimidine and bis-imide derivatives
SA Said, AEGE Amr, NM Sabry, MM Abdalla
文献索引：Said, Said A.; Amr, Abd El-Galil E.; Sabry, Nermien M.; Abdalla, Mohamed M. European Journal of Medicinal Chemistry, 2009 , vol. 44, # 12 p. 4787 - 4792
A series of diazipine, pyrimidine, fused triazolopyrimidine and imide derivatives were newly synthesized using 4-phenyl-but-3-en-2-one 1 as a starting material and compounds 2 and 9 are intermediates. Initially the acute toxicity of the compounds was assayed via the determination of their LD50. All the compounds were interestingly less toxic than the reference drug. The pharmacological screening showed that many of these obtained ...
