From N??Substituted Thioamides to Symmetrical and Unsymmetrical 3, 4, 5??Trisubstituted 4H??1, 2, 4??Triazoles: Synthesis and Characterisation of New Chelating …

MH Klingele, S Brooker

文献索引：Klingele, Marco H.; Brooker, Sally European Journal of Organic Chemistry, 2004 , # 16 p. 3422 - 3434

全文：HTML全文

被引用次数: 38

摘要

Abstract An improved protocol for the synthesis of N-substituted pyridine-2- thiocarboxamides under the conditions of the Willgerodt− Kindler reaction, employing a catalytic amount of sodium sulfide nonahydrate, has been developed. Following this protocol, eight thioamides carrying aromatic or aliphatic N-substituents have been prepared in good to excellent yields. Condensation of these thioamides or their S-alkylated ...