Tetrahedron letters

A synthesis of 2-and 4 (5)-(2-pyridinyl) imidazoles by palladium-catalysed cross-coupling reactions

AS Bell, DA Roberts, KS Ruddock

文献索引：Bell, A. S.; Roberts, D. A.; Ruddock, K. S. Tetrahedron Letters, 1988 , vol. 29, # 39 p. 5013 - 5016

全文：HTML全文

被引用次数: 54

摘要

Abstract N-Substituted imidazolylzinc chlorides were reacted with 2-bromopyridine in the presence of Pd (PPh 3) 4 and a two-fold excess of ZnCl 2 to afford cross-coupled products in 58–93% yields. Deprotection provided convenient routes to 2-or 4 (5)-(2-pyridinyl) imidazoles.