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举例 :可输入Filippa Pettersson 或者 Cancer Res. 75(6) , 1102-12, (2015) 或者10.1002/anie.201600521

Analgetic-antiinflammatory activity of prenyl derivatives of basic naphthylalkylnitriles and naphthylalkylamides chemically related to naphthypramide

G Pala, A Donetti, B Lumachi…

文献索引：Pala,G. et al. Journal of Medicinal Chemistry, 1973 , vol. 16, # 6 p. 720 - 723

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被引用次数: 1

摘要

In marked contrast, in the S series progressive alkyl substitution causes an initial decrease in pDp value with DMD and this is approximately equal in both the R and S series. Additional alkyl substitution produces no further change in pD2 but rather causes a progressive decrease in ia (Figure

1-NAPHTHALENEACETONITRILE, alpha-(2-(DIMETHYLAMINO)ETHYL)-结构式

1-NAPHTHALENEAC...

~%

1-Naphthaleneacetamide,a-[2-(dimethylamino)ethyl]-a-(3-methyl-2-buten-1-yl)-结构式

1-Naphthaleneac...

1-溴-3-甲基-2-丁烯结构式

1-溴-3-甲基-2-丁烯

~%

1-Naphthaleneacetamide,a-[2-(dimethylamino)ethyl]-a-(3-methyl-2-buten-1-yl)-结构式

1-Naphthaleneac...

1-Diprenylamino-2-hydroxyaethan结构式

1-Diprenylamino...

~%

α,α-Bis[2-[bis(3-methyl-2-butenyl)amino]ethyl]-1-naphthaleneacetamide结构式

α,α-Bis[2-[bis(...

(-)-4-aza-3-oxa-4-benzyl-2-spiro(1',3'-dithiane-[1'S,3'S]-1',3'-dioxo)-[5R,9S]-bicyclo[3.3.0] octane结构式

(-)-4-aza-3-oxa...

~%

α,α-Bis[2-[bis(3-methyl-2-butenyl)amino]ethyl]-1-naphthaleneacetamide结构式

α,α-Bis[2-[bis(...

1-溴-3-甲基-2-丁烯结构式

1-溴-3-甲基-2-丁烯

~%

α,α-Bis[2-[bis(3-methyl-2-butenyl)amino]ethyl]-1-naphthaleneacetamide结构式

α,α-Bis[2-[bis(...

1-Naphthaleneacetonitrile,a,a-bis[2-[bis(3-methyl-2-buten-1-yl)amino]ethyl]-结构式

1-Naphthaleneac...

~%

α,α-Bis[2-[bis(3-methyl-2-butenyl)amino]ethyl]-1-naphthaleneacetamide结构式

α,α-Bis[2-[bis(...

1-萘乙腈结构式

~%

α,α-Bis[2-[bis(3-methyl-2-butenyl)amino]ethyl]-1-naphthaleneacetamide结构式

α,α-Bis[2-[bis(...

1-Naphthaleneacetonitrile, alpha-(2-(bis(3-methyl-2-butenyl)amino)ethyl)-结构式

1-Naphthaleneac...

~%

α,α-Bis[2-[bis(3-methyl-2-butenyl)amino]ethyl]-1-naphthaleneacetamide结构式

α,α-Bis[2-[bis(...

2-(2-(bis(3-methylbut-2-en-1-yl)amino)ethyl)-5-methyl-2-(naphthalen-1-yl)hex-4-enenitrile结构式

2-(2-(bis(3-met...

~%

Acetamide, 2-(2-di(3-methyl-2-butenyl)amino)ethyl-2-(3-methyl-2-butenyl)-2-(1-naphthyl)-结构式

Acetamide, 2-(2...

1-Diprenylamino-2-hydroxyaethan结构式

1-Diprenylamino...

~%

Acetamide, 2-(2-di(3-methyl-2-butenyl)amino)ethyl-2-(3-methyl-2-butenyl)-2-(1-naphthyl)-结构式

Acetamide, 2-(2...

(-)-4-aza-3-oxa-4-benzyl-2-spiro(1',3'-dithiane-[1'S,3'S]-1',3'-dioxo)-[5R,9S]-bicyclo[3.3.0] octane结构式

(-)-4-aza-3-oxa...

~%

Acetamide, 2-(2-di(3-methyl-2-butenyl)amino)ethyl-2-(3-methyl-2-butenyl)-2-(1-naphthyl)-结构式

Acetamide, 2-(2...

未登录结构式

~%

Acetamide, 2-(2-di(3-methyl-2-butenyl)amino)ethyl-2-(3-methyl-2-butenyl)-2-(1-naphthyl)-结构式

Acetamide, 2-(2...

1-溴-3-甲基-2-丁烯结构式

1-溴-3-甲基-2-丁烯

~%

Acetamide, 2-(2-di(3-methyl-2-butenyl)amino)ethyl-2-(3-methyl-2-butenyl)-2-(1-naphthyl)-结构式

Acetamide, 2-(2...

1-Diprenylamino-2-hydroxyaethan结构式

1-Diprenylamino...

~%

1-Naphthaleneacetonitrile,a,a-bis[2-[bis(3-methyl-2-buten-1-yl)amino]ethyl]-结构式

1-Naphthaleneac...

1-溴-3-甲基-2-丁烯结构式

1-溴-3-甲基-2-丁烯

~%

1-Naphthaleneacetonitrile,a,a-bis[2-[bis(3-methyl-2-buten-1-yl)amino]ethyl]-结构式

1-Naphthaleneac...

1-萘乙腈结构式

~%

1-Naphthaleneacetonitrile,a,a-bis[2-[bis(3-methyl-2-buten-1-yl)amino]ethyl]-结构式

1-Naphthaleneac...

(-)-4-aza-3-oxa-4-benzyl-2-spiro(1',3'-dithiane-[1'S,3'S]-1',3'-dioxo)-[5R,9S]-bicyclo[3.3.0] octane结构式

(-)-4-aza-3-oxa...

~%

1-Naphthaleneacetonitrile,a,a-bis[2-[bis(3-methyl-2-buten-1-yl)amino]ethyl]-结构式

1-Naphthaleneac...

(-)-4-aza-3-oxa-4-benzyl-2-spiro(1',3'-dithiane-[1'S,3'S]-1',3'-dioxo)-[5R,9S]-bicyclo[3.3.0] octane结构式

(-)-4-aza-3-oxa...

1-Naphthaleneacetonitrile, alpha-(2-(bis(3-methyl-2-butenyl)amino)ethyl)-结构式

1-Naphthaleneac...

~%

1-Naphthaleneacetonitrile,a,a-bis[2-[bis(3-methyl-2-buten-1-yl)amino]ethyl]-结构式

1-Naphthaleneac...

1-溴-3-甲基-2-丁烯结构式

1-溴-3-甲基-2-丁烯

~%

1-Naphthaleneacetamide, alpha-(2-ethylmethylaminoethyl)-alpha-(3-methyl-2-butenyl)-结构式

1-Naphthaleneac...

α-[2-(Diethylamino)ethyl]-1-naphthaleneacetonitrile结构式

α-[2-(Diethylam...

~%

2-(2-diethylaminoethyl)-5-methyl-2-naphthalen-1-yl-hex-4-enamide结构式

2-(2-diethylami...

1-溴-3-甲基-2-丁烯结构式

1-溴-3-甲基-2-丁烯

~%

2-(2-diethylaminoethyl)-5-methyl-2-naphthalen-1-yl-hex-4-enamide结构式

2-(2-diethylami...

1-溴-3-甲基-2-丁烯结构式

1-溴-3-甲基-2-丁烯

~%

Acetamide, 2-(3-methyl-2-butenyl)-2-(2-morpholineethyl)-2-(1-naphthyl)-结构式

Acetamide, 2-(3...

1-Diprenylamino-2-hydroxyaethan结构式

1-Diprenylamino...

~%

1-Naphthaleneacetonitrile, alpha-(2-(bis(3-methyl-2-butenyl)amino)ethyl)-结构式

1-Naphthaleneac...

1-溴-3-甲基-2-丁烯结构式

1-溴-3-甲基-2-丁烯

~%

1-Naphthaleneacetonitrile, alpha-(2-(bis(3-methyl-2-butenyl)amino)ethyl)-结构式

1-Naphthaleneac...

1-萘乙腈结构式

(-)-4-aza-3-oxa-4-benzyl-2-spiro(1',3'-dithiane-[1'S,3'S]-1',3'-dioxo)-[5R,9S]-bicyclo[3.3.0] octane结构式

(-)-4-aza-3-oxa...

~%

1-Naphthaleneacetonitrile, alpha-(2-(bis(3-methyl-2-butenyl)amino)ethyl)-结构式

1-Naphthaleneac...

1-Naphthaleneacetonitrile, alpha-(2-(bis(3-methyl-2-butenyl)amino)ethyl)-结构式

1-Naphthaleneac...

~%

Acetamide, 2-(2-di(3-methyl-2-butenyl)amino)ethyl-2-(1-naphthyl)-结构式

Acetamide, 2-(2...

1-萘乙腈结构式

~%

Acetamide, 2-(2-di(3-methyl-2-butenyl)amino)ethyl-2-(1-naphthyl)-结构式

Acetamide, 2-(2...

1-Diprenylamino-2-hydroxyaethan结构式

1-Diprenylamino...

~%

Acetamide, 2-(2-di(3-methyl-2-butenyl)amino)ethyl-2-(1-naphthyl)-结构式

Acetamide, 2-(2...

(-)-4-aza-3-oxa-4-benzyl-2-spiro(1',3'-dithiane-[1'S,3'S]-1',3'-dioxo)-[5R,9S]-bicyclo[3.3.0] octane结构式

(-)-4-aza-3-oxa...

~%

Acetamide, 2-(2-di(3-methyl-2-butenyl)amino)ethyl-2-(1-naphthyl)-结构式

Acetamide, 2-(2...

1-溴-3-甲基-2-丁烯结构式

1-溴-3-甲基-2-丁烯

~%

Acetamide, 2-(2-di(3-methyl-2-butenyl)amino)ethyl-2-(1-naphthyl)-结构式

Acetamide, 2-(2...