Synthetic studies towards paspalicine: Preliminary investigations, and the synthesis of 3′, 4′, 7′, 7′ a, 9′, 10′, 11′, 11′ a-octahydro-4′, 4′, 7′ a- …
A Ali, SD Guile, JE Saxton, M Thornton-Pett
文献索引：Ali, Amin; Guile, Simon D.; Edwin Saxton; Thornton-Pett, Mark Tetrahedron, 1991 , vol. 47, # 32 p. 6407 - 6426
Preliminary investigations directed towards the synthesis of the indole-diterpene mould metabolite, paspalicine 1, are described. Following the preparation of the β-pyrone ketal 7, which contains the characteristic functional group of paspalicine, the compound 25, which constitutes rings D–G of paspalicine with the correct relative stereochemistry, has been synthesised in eight steps from the monoketal 12 of the Wieland-Miescher ketone, in an ...
