Abstract A series of novel 3-(2, 4, 6-trisubstituted phenyl) uracil derivatives has been synthesised and assayed for insecticidal/acaricidal activity. The assay indicated certain requirements for optimal insecticidal activity, which can be summarised as follows:(a) the substituents on the phenyl ring should possess hydrophobicity and electron-withdrawing properties, and the sum of their volumes determines the level of activity;(b) the substituent ...