Abstract This article describes the synthesis of long-chain 1-alkylimidazole-2-thiols 3 and 1- decylbenzimidazole-2-thiol (10), of value as nucleophilic scavengers for sulfenyl groups (RS+) in lipophilic membranes 2) and as inhibitors of thyroid peroxidase 3), as well as of the corresponding 1-alkylimidazoles 6 and-benzimidoles 7. Because 1-decyl compounds belonging to the benzimidazole series apparently have a specific action on proton ...