Halogenation Using N-Halogenocompounds. II. Acid Catalyzed Bromination of Aromatic Compounds with 1, 3-Dibromo-5, 5-dimethylhydantoin.
…, H Kawaguchi, S Yoshinaga, A Nishida…
文献索引：Eguchi, Hisao; Kawaguchi, Hideichiro; Yoshinaga, Sachiyo; Nishida, Akiko; Nishiguchi, Takeshi; Fujisaki, Shizuo Bulletin of the Chemical Society of Japan, 1994 , vol. 67, # 7 p. 1918 - 1921
Ring bromination of aromatic compounds using 1, 3-dibromo-5, 5-dimethylhydantoin in dichloromethane is promoted by the addition of strong acids. Both organic and inorganic acids whose pK a values are lower than-2 showed the promoting effect. This acid-catalyzed bromination is both practical and effective, even for aromatics having electron-withdrawing substituents.
