Tetrahedron Letters

Intermolecular Friedel–Crafts reaction catalyzed by InCl 3

M Kaneko, R Hayashi, GR Cook

文献索引：Kaneko, Miho; Hayashi, Ryuji; Cook, Gregory R. Tetrahedron Letters, 2007 , vol. 48, # 40 p. 7085 - 7087

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被引用次数: 25

摘要

Our recent discovery that In (III) salts were able to activate halides catalytically under mild conditions for the intermolecular Friedel–Crafts cyclization prompted us to explore this highly efficient activation in intermolecular Friedel–Crafts reactions. The alkylation of p-xylene with allylic and benzylic halides was demonstrated under catalytic and mild condition to afford in some cases quantitative yields of the monoalkylated products without the need to employ ...