Heteroatom Chemistry

Utilization of α??halocarbonyl compounds in the synthesis of thiazole, thiadiazole, and thiophene derivatives

E Abdel??Latif, S Bondock

文献索引：Abdel-Latif, Ehab; Bondock, Samir Heteroatom Chemistry, 2006 , vol. 17, # 4 p. 299 - 305

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被引用次数: 22

摘要

Abstract The behavior of ethyl 2-phenylthiocarb-amoyl acetate 1 toward a variety of several α-halo-carbonyl compounds was investigated. Thus, reaction of 1 with α-bromoketones, hydrazonoyl bromides, and 2-chloro-N-arylacetamides afforded the corresponding dihydrothiazole, 1, 3, 4-thiadiazole, and thiophene derivatives, respectively. The synthesis of thiazolidin-4-one 11, thiazolidin-5-one 12, and some azo derivatives of thiazolidin-5-one ...