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A catch-and-release strategy for the combinatorial synthesis of 4-acylamino-1, 3-thiazoles as potential CDK5 inhibitors

SD Larsen, CF Stachew, PM Clare, JW Cubbage…

文献索引:Bioorganic and Medicinal Chemistry Letters, , vol. 13, # 20 p. 3491 - 3495

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被引用次数: 19

摘要

... Bioorganic & Medicinal Chemistry Letters. ... Preliminary medicinal chemistry work (not shown) on 4 quickly established that simple urea or hydrazide analogues were not active, indicating that the aminourea moiety was important. ...

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