Tetrahedron

Acyl hydrazines as precursors to acyl radicals

R Braslau, MO Anderson, F Rivera, A Jimenez…

文献索引：Braslau, Rebecca; Anderson, Marc O; Rivera, Frank; Jimenez, Armando; Haddad, Terra; Axon, Jonathan R Tetrahedron, 2002 , vol. 58, # 27 p. 5513 - 5523

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被引用次数: 44

摘要

The use of acyl hydrazines (hydrazides) as precursors for the stoichiometric generation of acyl radicals is explored. Two classes of substrates are examined: unsubstituted acyl hydrazines and acyl hydrazines substituted with a leaving group (2-nitrobenzenesulfonyl or 'nosyl'). Both types are successfully converted to acyl radicals, and are then trapped by nitroxide radicals to give acyloxyamine products. Cyclization reactions are demonstrated ...