Novel synthetic route of coelenterazines-2-: Synthesis of various dehydrocoelenterazine analogs

…, M Kuse, T Mutarapat, N Thasana…

文献索引：Kondo, Nobuhiro; Kuse, Masaki; Mutarapat, Thumnoon; Thasana, Nopporn; Isobe, Minoru Heterocycles, 2005 , vol. 65, # 4 p. 843 - 856

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被引用次数: 5

摘要

Abstract–The novel synthetic route to introduce various substituents into 5-position of coelenteramine is described. Difficulties, however, are observed in the attempted synthesis of some analogs having labile functional groups. This is due to the strong acid conc. H2SO4 after Suzuki-Miyaura coupling, so that the route was limited only to the synthesis for aminopyrazines having acid-stable functional groups. In this report, we describe ...