Synthesis, Decarboxylation, and Nitrosation of 1??Acyl??2??pyrrolidone??3??carboxylic Acids: A Convenient Novel Entry to 2, 3??Dioxopyrrolidine Derivatives
V Gailius, H Stamm
文献索引：Gailius; Stamm Archiv der Pharmazie, 1992 , vol. 325, # 2 p. 89 - 92
Abstract Esters 1 of 1-acyl-2-pyrrolidone-3-carboxylic acids 2 were hydrolized to 2 with acetic acid/HCl at 60–70 C. Reaction of 1a with formic acid/HCl at 60–75 C led to (not isolated) 2a which began to decarboxylate to 3a during the conversion of 1a to 2a even at
