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Initiation of DNA strand cleavage by 1, 2, 4-benzotriazine 1, 4-dioxide antitumor agents: mechanistic insight from studies of 3-methyl-1, 2, 4-benzotriazine 1, 4-dioxide

V Junnotula, U Sarkar, S Sinha…

文献索引:Khodja, Mohamed; Moulay, Saad; Boutoumi, Hocine; Wilde, Horst Heteroatom Chemistry, 2006 , vol. 17, # 2 p. 166 - 172

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被引用次数: 35

摘要

... Volume: Page: ... The dehydration process proposed for the formation of 4 finds some general precedent in radiation chemistry (Scheme 4). In ... drugs may be facilitated by improved understanding of the molecular mechanisms by which this new chemical class of ...