Triple-helical transition state analogues: a new class of selective matrix metalloproteinase inhibitors

…, K Brew, JK Whitehead, S Li, RP Hammer…

文献索引：Li, Shunzi; Whitehead, John K.; Hammer, Robert P. Journal of Organic Chemistry, 2007 , vol. 72, # 8 p. 3116 - 3118

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被引用次数: 42

摘要

Alterations in activities of one family of proteases, the matrix metalloproteinases (MMPs), have been implicated in primary and metastatic tumor growth, angiogenesis, and pathological degradation of extracellular matrix (ECM) components, such as collagen and