Chemistry Letters

Halogenation of Aromatic Compounds by N-chloro-, N-bromo-, and N-iodosuccinimide

K Tanemura, T Suzuki, Y Nishida, K Satsumabayashi…

文献索引：Tanemura, Kiyoshi; Suzuki, Tsuneo; Nishida, Yoko; Satsumabayashi, Koko; Horaguchi, Takaaki Chemistry Letters, 2003 , vol. 32, # 10 p. 932 - 933

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被引用次数: 97

摘要

Halogenation of aromatic compounds is one of the most im- portant reactions in organic synthesis. The most commonly used reagents for this purpose are bromine and chlorine in the pres- ence of iron halide. In terms of ease of handling in laboratories, N-bromo- (NBS) and N-chlorosuccinimide (NCS) will be supe- rior halogenating reagents if benzylic halogenation is sup- pressed. Schmid reported that benzene and toluene gave nuclear brominated ...