Tetrahedron letters

A stannous chloride-induced deacetalisation–cyclisation process to prepare the ABC ring system of'upenamide

M Reid, RJK Taylor

文献索引：Reid, Mark; Taylor, Richard J. K. Tetrahedron Letters, 2004 , vol. 45, # 21 p. 4181 - 4183

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被引用次数: 18

摘要

Upenamide 1 is a unique macrocyclic alkaloid isolated 1 from the branching sponge, Echinochalina sp. (Protolithospongia) (order Poecilosclerida) collected from Derawan Island, Indonesia. Due to the scarcity of the natural product the biological activity of 'upenamide has not yet been widely screened although no anticancer activity was seen in in vitro screening. The name 'upenamide is coined from `upena', meaning fishing net or trap in Hawaiiwan, and reflects its ...