Tetrahedron

Epoxidation with dioxiranes derived from 2-fluoro-2-substituted-1-tetralones and-1-indanones

DS Brown, BA Marples, P Smith, L Walton

文献索引：Brown, David S.; Marples, Brian A.; Smith, Paul; Walton, Lesley Tetrahedron, 1995 , vol. 51, # 12 p. 3587 - 3606

全文：HTML全文

被引用次数: 109

摘要

Homochiral 2-fluoro-2-substituted-1-tetralones (10a, 10b, 13) and ethyl 2-fluoro-1-indanone- 2-carboxylate (16) have been isolated. The dioxirane derivatives of these ketones have been prepared in situ, and have been shown to epoxidise alkenes but not enantioselectively. The dioxirane derivative of methyl 2, 5, 7-trifluoro-1-indanone-2- carboxylate (18) has been shown to be comparatively efficient in epoxidation.