前往化源商城

Tetrahedron

Regiospecific synthesis of mono-and bicyclic 6-alkoxy-2-pyrones and their use in the preparation of substituted aromatics, anthraquinones, and tetracyclic …

ME Jung, JA Lowe, MA Lyster, M Node, RW Pfluger…

文献索引:Jung; Lowe III; Lyster; et al. Tetrahedron, 1984 , vol. 40, # 22 p. 4751 - 4766

全文:HTML全文

被引用次数: 51

摘要

Several mono-and bicyclic 6-methoxy-2-pyrones having substituents at C4 and C5 can be prepared regiospecifically by either of two routes:(1) regiospecific construction of a glutaconic half-ester followed by dehydrative cyclization, and (2) regiospecific Friedel-Crafts acylation of 6-methoxy-2-pyrones at C5. These pyrones undergo clean and regiospecific Diels-Alder cycloadditions with various unsymmetrical dienophiles, eg, quinones, ...

 相关合成线路

~99%

~%

~%

~%

~%

~%

~%

~%

~82%

~%

~41%

~%

~%

~87%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~89%

~77%

~%

~%

~%

~13%

~%

~%

~%

~98%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%