2, 3-Dihydrobenzofuran analogs of hallucinogenic phenethylamines

…, SE Snyder, R Oberlender, MP Johnson…

文献索引：Nichols; Snyder; Oberlender; Johnson; Huang Journal of Medicinal Chemistry, 1991 , vol. 34, # 1 p. 276 - 281

全文：HTML全文

被引用次数: 51

摘要

Two 2, 3-dihydrobenzofuran analogues of hallucinogenic amphetamines were prepared and evaluated for activity in the two-lever drug-discrimination paradigm in rats trained to discriminate saline from LSD tartrate (0.08 mg/kg) and for the ability to displace [1251]-(R)- DOI ([125I]-(R)-1-(2, 5-dimethoxy-4-iodophenyl)-2-aminopropane) from rat cortical homogenate 5-HT2 receptors. The compounds, 1-(5-methoxy-2, 3-dihydrobenzofuran-4- ...