Pyrimidines. XIX. Pyrimido [4, 5??e] dihydro??1, 3??oxazines and related compounds

DE O'Brien, LT Weinstock, RH Springer…

文献索引：O'Brien,D.E. et al. Journal of Heterocyclic Chemistry, 1967 , vol. 4, p. 49 - 53

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被引用次数: 2

摘要

Abstract A number of 2-substituted 4, 5-dihydroxy-6-(substituted aminomethyl) pyrimidines (VIII) were prepared from the corresponding 2-substituted 4, 5-dihydroxypyrimidines (VII) by a new pyrimidine Mannich reaction. The structure of VIII was proved by an independent synthesis. Further study of this reaction led to the synthesis of a new class of compounds: the pyrimido [4, 5-e] dihydro-1, 3-oxazines (VI).