Isopropylidenemalononitrile in the synthesis of 2-amino-4, 6, 6-trimethylcyclohexa-2, 4-diene-1, 1, 3-tricarbonitrile, 6-amino-2-(4-methoxybenzoylmethylsulfanyl)-4, 4- …
VD Dyachenko, EB Rusanov
文献索引:Dyachenko; Rusanov Russian Journal of Organic Chemistry, 2006 , vol. 42, # 9 p. 1374 - 1379
Abstract Michael reactions of isopropylidenemalononitrile with cyanothioacetamide (in the presence of 4-methoxyphenacyl bromide), cyclohexane-1, 3-dione, and 4-hydroxycoumarin, gave 6-amino-2-(4-methoxy-benzoylmethylsulfanyl)-4, 4-dimethyl-1, 4-dihydropyridine-3, 5- dicarbonitrile, 2-amino-4, 4-dimethyl-5-oxo-5, 6, 7, 8-tetrahydro-4 H-chromene-3- carbonitrile, and 2-amino-4, 4-dimethyl-5-oxo-4 H, 5 H-pyrano [3, 2-c]-chromene-3- ...