One??Pot Synthesis of 4, 6??Diaryl??2??oxo??1, 2??dihydropyridine??3??carbonitriles via Three??Component Cyclocondensation under Solvent??Free Conditions
Abstract An efficient and facile synthesis of 4, 6??diaryl??2??oxo??1, 2??dihydropyridine??3?? carbonitriles via three??component cyclocondensation from aromatic aldehydes, aromatic ketones, and 2??cyanoacetamide under solvent??free conditions is described. The mild reaction conditions, simple protocol, and clean reaction make this protocol practical and economically attractive.
